UK-based biotech company Small Pharma has conducted the first ever placebo-controlled study exploring DMT as a potential treatment for depression.
Study participants were given either placebo or an intervenous infusion of synthetic DMT, followed by supportive therapy.
Those in the treatment group reported a lasting reduction in symptoms. Dr. Carol Routledge, Small Pharma’s Chief Medical and Scientific Officer explains:
“We are pleased that a significant number of patients benefited from the treatment in our trial. SPL026 with supportive therapy was shown to have a significant antidepressant effect that was rapid and durable, with a remission rate of 57% at three months following a single dose of SPL026.
It was encouraging to see that SPL026 demonstrated a favourable safety and tolerability profile in MDD patients in this study, consistent with our Phase I study. The results are clinically meaningful and enable us to progress into an international multi-site Phase IIb study where we seek to further explore the efficacy and safety profile of SPL026 in a larger MDD patient population.”
Lion’s mane mushrooms have gained popularity in recent years for their potential health benefits. These fascinating fungi have become a staple in many natural wellness communities, leaving some to wonder: is lion’s mane a psychedelic? The short answer is no. Lion’s mane mushrooms do not contain any psychedelic properties. That doesn’t mean they aren’t beneficial though.
Adaptogens are special plants and fungi that can help your body adapt to stress. They work by helping the body cope with physical and psychological
Adrenal fatigue is a condition naturopathic doctors often point to when patients show symptoms of chronic exhaustion, and recommending adaptogens for adrenal fatigue is relatively common practice. But is adrenal fatigue a real diagnosis? Here’s what you need to know about the condition, what western medicine has to say about it, and how adaptogens may be able to help with symptoms.
At the most basic level, comparing functional mushrooms vs. psychedelic mushrooms comes down to the presence of hallucinogenic effects. Psychedelic mushrooms have psychoactive effects and can produce a “trip”, whereas functional mushrooms do not. Both types of mushrooms can offer both physical and mental health benefits, but the specific effects they have on the mind and body are very different.
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